Different types of TMS exist because researchers have discovered various ways to optimize the delivery of magnetic pulses. Each approach varies in pulse frequency, intensity, and targeting method, allowing clinicians to customize treatment based on individual patient needs and specific mental health conditions.
Repetitive TMS (rTMS)
Repetitive transcranial magnetic stimulation (rTMS), represents the original and most widely studied form of TMS therapy. The Food and Drug Administration (FDA) first approved rTMS for treating depression in 2008, making it the foundation of modern TMS treatment.
rTMS delivers magnetic pulses in repetitive patterns, typically at high frequencies (10-20 Hz) or low frequencies (1 Hz). High-frequency stimulation generally excites brain activity, while low-frequency stimulation tends to inhibit it. This flexibility allows clinicians to target different brain regions based on the specific mental health condition being treated.
The standard rTMS protocol involves treatment sessions lasting 30-40 minutes, conducted five days per week for four to six weeks. rTMS has demonstrated significant effectiveness in treating depression, with studies showing response rates of 50-60% in patients with treatment resistant depression.
Deep TMS (dTMS)
Deep TMS (dTMS) represents an advancement in TMS technology, utilizing specialized H-coils to penetrate deeper into brain tissue. Unlike traditional rTMS, which primarily affects surface brain regions, dTMS can stimulate areas up to 6 centimeters below the skull surface.
This deeper penetration may be particularly beneficial for patients who haven’t responded well to traditional rTMS treatment. dTMS treatment sessions typically last 20 minutes and follow a similar schedule to rTMS, with five sessions per week for four to six weeks.
Intermittent Theta Burst Stimulation (iTBS)
This innovative approach mimics the brain’s natural theta rhythm, delivering pulses in specific patterns that may enhance neuroplasticity more effectively than traditional methods.
iTBS sessions are remarkably brief, lasting only 3-10 minutes compared to the 30-40 minutes required for standard rTMS. Despite the shorter duration, iTBS delivers the same therapeutic benefit as longer treatment sessions, making it an attractive option for busy patients.