Scottsdale TMS offers FDA-approved Spravato® (esketamine) therapy for adults struggling with treatment-resistant depression and severe mood disorders. Our outpatient psychiatry clinic in Scottsdale, AZ provides Spravato in a medically supervised environment led by a licensed psychiatrist and specialized mental health team experienced in interventional depression care.
For patients who have not achieved relief from traditional antidepressants, Spravato represents a breakthrough option—targeting the brain in a fundamentally different way and often producing improvement when standard medications have failed.
Spravato is a prescription nasal spray derived from ketamine and approved by the FDA for treatment-resistant depression and major depressive disorder with acute suicidal thoughts. Unlike SSRIs and SNRIs that work primarily on serotonin and norepinephrine, esketamine acts on the glutamate system, helping to repair disrupted neural communication and restore healthy brain network function.
Many patients notice changes in mood, clarity, and emotional stability within days rather than weeks, making Spravato one of the fastest-acting depression treatments available in outpatient psychiatry today.
Spravato stimulates NMDA receptor pathways that promote synaptic growth and neuroplasticity—the brain’s ability to form new, healthier connections. This can lead to:
Because of its potency and unique mechanism, Spravato is administered only in REMS-certified medical clinics under continuous clinical monitoring.
Our Scottsdale outpatient psychiatry center combines advanced technology with physician-led care:
Spravato may be appropriate for individuals who:
Each Spravato session at Scottsdale TMS includes:
Our goal is not only symptom relief, but long-term stabilization and restored quality of life through advanced, evidence-based depression treatment in Scottsdale, Arizona.