Spravato (Esketamine)
in Paradise Valley, AZ
At Scottsdale TMS & Spravato, we offer hope for individuals with treatment-resistant depression in the Paradise Valley, AZ area. Spravato (esketamine) is an innovative, FDA-approved nasal spray that can provide rapid relief for adults who have not responded to other antidepressants. Our comfortable Scottsdale clinic offers a path to renewed well-being under the care of board-certified psychiatrists dedicated to providing compassionate, effective mental health solutions.
What Is Spravato (Esketamine)?
Rapid-Acting Relief
Unlike traditional antidepressants that may take weeks to show effects, Spravato can deliver noticeable improvements in depressive symptoms within days. This rapid onset offers new hope for those in urgent need of relief.
Targeted Brain Pathway
Spravato works differently from most oral antidepressants by targeting the brain’s NMDA receptor. This mechanism is believed to help restore synaptic connections in brain cells of people with major depressive disorder.
Non-Invasive Nasal Spray
The treatment is administered as a simple nasal spray that you use yourself in our clinic. This method is non-invasive and allows for direct delivery of the medication without injections or complex procedures.
Medically Supervised Treatment
Each treatment is administered in our REMS-certified clinic under the direct supervision of our trained medical staff. We monitor you for at least two hours after administration to ensure your safety and comfort, adhering to strict FDA safety protocols.
Insurance Navigation Support
Our dedicated team helps you navigate the complexities of insurance coverage. We assist with verifying your benefits, handling prior authorizations, and explaining your expected costs, so you can focus on your recovery.
Comfortable & Private Setting
We provide treatment in a comfortable, private suite designed to create a calm and reassuring atmosphere. Your well-being is our priority, and our environment supports a positive therapeutic experience.
FDA-Approved Indications
Spravato is an FDA-approved medication for adults with either treatment-resistant depression (TRD) or major depressive disorder (MDD) with acute suicidal thoughts or behaviors.
Our Spravato (Esketamine)Process

Initial Psychiatric Consultation
Your journey begins with a comprehensive evaluation by one of our board-certified psychiatry providers. We will review your medical history, past treatments, and current symptoms to determine if Spravato is an appropriate and safe option for you.
Insurance Verification & Authorization
Once you are approved as a candidate, our administrative team will work with your insurance provider. We manage the prior authorization process and clarify your coverage to ensure transparency about the financial aspects of your treatment plan.
Preparing for Your Treatment Day
On the day of your appointment, please arrange for transportation home, as you will not be able to drive. Upon arrival, our clinical team will conduct a brief pre-treatment screening, including checking your blood pressure, to ensure you are ready.
Supervised Self-Administration
You will relax in a private treatment suite and administer the Spravato nasal spray yourself under the guidance of our medical staff. Our team will be present to ensure you are comfortable and to monitor the process.
Post-Treatment Observation & Care
Following administration, you will rest in our clinic for a mandatory two-hour observation period. Our medical staff will monitor your response and vital signs to ensure your safety. We also coordinate ongoing psychiatric care to support your long-term wellness.

Expert, Physician-Led Psychiatric Care
Our treatment team at Scottsdale TMS & Spravato is led by board-certified psychiatrists with specialized expertise in managing complex mood disorders. We are dedicated to offering compassionate, evidence-based care and collaborate with your existing healthcare providers to ensure a comprehensive and integrated treatment plan.

Who Benefits from Spravato (Esketamine)?
At Scottsdale TMS & Spravato, we offer hope for individuals with treatment-resistant depression in the Paradise Valley, AZ area. Spravato (esketamine) is an innovative, FDA-approved nasal spray that can provide rapid relief for adults who have not responded to other antidepressants. Our comfortable Scottsdale clinic offers a path to renewed well-being under the care of board-certified psychiatrists dedicated to providing compassionate, effective mental health solutions.
Conditions We Treat

- Diagnosed with Treatment-Resistant Depression (TRD)
- Experiencing Major Depression with Suicidal Thoughts
- Tried Two or More Oral Antidepressants Without Success
- Seeking a Treatment with Rapid-Acting Effects
- Able to Commit to the Required Treatment Schedule

Patient Experiences

“Scottsdale TMS has been an absolute blessing in my life. I receive Spravato treatments here, and I truly look forward to my appointments. The office is beautiful, exceptionally clean, and has a calm, welcoming atmosphere that immediately puts you at ease. The staff is what makes this place so special.”

“The staff is wonderful and the space is clean and comfortable!”

“Absolutely love this place! Alyssa, Maya and Jada are the best and are so flexible and helpful. TMS and Spravato have changed my life.”
Cost of Spravato (esketamine) Nasal Spray in Paradise Valley, AZ
At Scottsdale TMS & Spravato, we offer hope for individuals with treatment-resistant depression in the Paradise Valley, AZ area. Spravato (esketamine) is an innovative, FDA-approved nasal spray that can provide rapid relief for adults who have not responded to other antidepressants. Our comfortable Scottsdale clinic offers a path to renewed well-being under the care of board-certified psychiatrists dedicated to providing compassionate, effective mental health solutions.
FAQ About Spravato (Esketamine)
How is Spravato different from other antidepressants?
Spravato works on a different pathway in the brain—the NMDA receptor—than most common oral antidepressants. This unique mechanism is why it can provide relief much more quickly, often within days, for those who haven’t responded to other medications.
What happens during a Spravato treatment session?
During a session, you will relax in a private room at our clinic and self-administer the nasal spray under our staff’s guidance. Afterward, you will rest comfortably for a two-hour observation period while our medical team monitors your well-being.
Is Spravato treatment covered by my insurance?
Many major insurance plans, including Medicare, offer coverage for Spravato as it is an FDA-approved treatment for specific conditions. Our team specializes in navigating the insurance process and will help verify your benefits and obtain prior authorizations.
Why do I need to be monitored for two hours after treatment?
The two-hour monitoring period is an essential FDA safety requirement known as REMS (Risk Evaluation and Mitigation Strategy). This allows our medical team to monitor your blood pressure and ensure any potential side effects like sedation are managed in a safe, controlled environment.
Take the First Step
Toward Lasting Relief
You don't have to keep waiting for something to work.
Same-day appointments are available, most insurance
is accepted, and no referral is needed to get started.
Take the First
Step
Toward
Lasting Relief
You don't have to keep waiting for something to work.
Same-day appointments are available, most insurance
is accepted, and no referral is needed to get started.