Spravato (Esketamine)
in Phoenix, AZ
Scottsdale TMS & Spravato provides innovative spravato (esketamine) nasal spray in Phoenix, AZ, for adults with treatment-resistant depression. For Phoenix area residents seeking an alternative to traditional antidepressants, our clinic provides a fast-acting, FDA-approved therapy in a supportive, medically supervised environment. Located a convenient drive away, our board-certified psychiatrists are dedicated to helping you find lasting relief and reclaim your well-being.
What Is Spravato (esketamine) nasal spray in Phoenix, AZ?
Rapid-Acting Relief
Unlike conventional antidepressants that can take weeks or months to become effective, Spravato can produce noticeable improvements in mood and depressive symptoms within days. This rapid onset provides new hope for individuals seeking immediate change.
FDA-Approved & REMS Certified
Spravato is an FDA-approved treatment for specific depressive disorders. Our clinic is REMS (Risk Evaluation and Mitigation Strategy) certified, ensuring we meet the highest federal safety standards for its administration and monitoring.
Simple Nasal Spray Administration
Treatment is delivered via a simple, self-administered nasal spray, eliminating the need for injections or more invasive procedures. This non-invasive method is performed under the direct supervision of our clinical team to ensure safety and proper dosage.
Supervised in a Comfortable Setting
Your safety and comfort are paramount. We provide a private, tranquil treatment suite for each session, where our medical staff remains present to provide support and ensure a positive, secure experience.
Targets a Different Brain Pathway
Spravato works by targeting the brain’s NMDA receptor, which is different from the mechanism of most oral antidepressants. This unique action helps restore synaptic connections in the brain, offering a new approach for those who haven’t found relief with other treatments.
Insurance and Access Support
Most major insurance plans, including Medicare, cover Spravato treatment. Our dedicated team assists with navigating the prior authorization process and clarifying your benefits to make this advanced care more accessible.
Integrated Psychiatric Care
Spravato is part of our comprehensive approach to mental wellness. We often integrate this therapy with ongoing medication management and other treatments to support your long-term stability and recovery.
Our Spravato (esketamine) nasal spray Process

Comprehensive Psychiatric Evaluation
Your journey begins with a thorough evaluation by one of our psychiatric providers. We review your mental health history, past treatments, and current symptoms to determine if Spravato is an appropriate option for you.
Personalized Treatment Planning
If you are a candidate, we develop a personalized treatment plan. This includes scheduling your initial series of sessions and coordinating all necessary insurance authorizations on your behalf.
Supervised Treatment Session
On treatment day, you will relax in a private suite and self-administer the nasal spray under our team’s guidance. We monitor your vital signs and overall comfort throughout the appointment.
Post-Treatment Observation
Following administration, a mandatory two-hour observation period is required in our clinic. This ensures your safety as the medication’s immediate effects subside before you are cleared to be driven home.
Ongoing Follow-Up Care
Our team provides continuous psychiatric follow-up to monitor your progress and make any necessary adjustments to your overall treatment plan. We work collaboratively with you to sustain your improvements and support long-term wellness.

Our Compassionate Care Team
Our Spravato treatment program is overseen by board-certified psychiatrists and licensed psychiatric providers with deep expertise in complex mood disorders. This specialized team is trained in interventional depression care and is committed to providing a safe, empathetic, and effective treatment experience. We prioritize a collaborative approach, ensuring your care is tailored to your unique needs and goals.

Who Benefits from Spravato (esketamine) nasal spray?
Scottsdale TMS & Spravato provides innovative spravato (esketamine) nasal spray in Phoenix, AZ, for adults with treatment-resistant depression. For Phoenix area residents seeking an alternative to traditional antidepressants, our clinic provides a fast-acting, FDA-approved therapy in a supportive, medically supervised environment. Located a convenient drive away, our board-certified psychiatrists are dedicated to helping you find lasting relief and reclaim your well-being.
Conditions We Treat

- Treatment-Resistant Depression (TRD)
- Major Depressive Disorder (MDD)
- Major Depressive Disorder with Suicidal Thoughts
- Adults with Inadequate Response to Other Therapies
- Patients Augmenting Their Oral Antidepressant

Patient Experiences

“Scottsdale TMS has been an absolute blessing in my life. I receive Spravato treatments here, and I truly look forward to my appointments. The office is beautiful, exceptionally clean, and has a calm, welcoming atmosphere that immediately puts you at ease. The staff is what makes this place so special.”

“The staff is wonderful and the space is clean and comfortable!”

Cost of Spravato (esketamine) nasal spray in Phoenix, AZ
Scottsdale TMS & Spravato provides innovative spravato (esketamine) nasal spray in Phoenix, AZ, for adults with treatment-resistant depression. For Phoenix area residents seeking an alternative to traditional antidepressants, our clinic provides a fast-acting, FDA-approved therapy in a supportive, medically supervised environment. Located a convenient drive away, our board-certified psychiatrists are dedicated to helping you find lasting relief and reclaim your well-being.
FAQ About Spravato (esketamine) nasal spray in Phoenix, AZ
How is Spravato different from traditional antidepressants?
Spravato works on the NMDA receptor pathway in the brain, which is different from how most oral antidepressants (like SSRIs) function. This allows it to often work much more quickly—within days instead of weeks—and may be effective for individuals who have not responded to other medications.
Is Spravato treatment covered by insurance?
Yes, Spravato is covered by most major insurance plans, including Medicare, for its approved uses. Our team will assist you with the prior authorization process and help you understand your specific coverage and potential out-of-pocket costs before beginning treatment.
What happens during a Spravato treatment session?
During your appointment, you will self-administer the nasal spray in a private, comfortable room under our team’s supervision. You will then relax for a two-hour monitoring period where we observe your response and ensure your safety before you are cleared to go home.
Do I need someone to drive me home after treatment?
Yes, you must have a trusted friend or family member drive you home after each session. You should not drive, operate heavy machinery, or make important decisions for the rest of the day following your treatment.
Take the First Step
Toward Lasting Relief
You don't have to keep waiting for something to work.
Same-day appointments are available, most insurance
is accepted, and no referral is needed to get started.
Take the First
Step
Toward
Lasting Relief
You don't have to keep waiting for something to work.
Same-day appointments are available, most insurance
is accepted, and no referral is needed to get started.