Spravato® Treatment at Scottsdale TMS
Advanced Esketamine Therapy for
Treatment-Resistant Depression
Scottsdale TMS offers FDA-approved Spravato® (esketamine) therapy for adults struggling with treatment-resistant depression and severe mood disorders. Our outpatient psychiatry clinic in Scottsdale, AZ provides Spravato in a medically supervised environment led by a licensed psychiatrist and specialized mental health team experienced in interventional depression care.
For patients who have not achieved relief from traditional antidepressants, Spravato represents a breakthrough option—targeting the brain in a fundamentally different way and often producing improvement when standard medications have failed.
What Is Spravato (Esketamine)?
Spravato is a prescription nasal spray derived from ketamine and approved by the FDA for treatment-resistant depression and major depressive disorder with acute suicidal thoughts. Unlike SSRIs and SNRIs that work primarily on serotonin and norepinephrine, esketamine acts on the glutamate system, helping to repair disrupted neural communication and restore healthy brain network function.
Many patients notice changes in mood, clarity, and emotional stability within days rather than weeks, making Spravato one of the fastest-acting depression treatments available in outpatient psychiatry today.
How Esketamine Therapy Supports Brain Recovery
Spravato stimulates NMDA receptor pathways that promote synaptic growth and neuroplasticity—the brain’s ability to form new, healthier connections. This can lead to:
- Reduction in persistent depressive symptoms
- Decreased suicidal ideation
- Improved emotional regulation
- Greater response to psychotherapy and medication
- Renewed motivation and cognitive flexibility
Because of its potency and unique mechanism, Spravato is administered only in REMS-certified medical clinics under continuous clinical monitoring.
Why Choose Scottsdale TMS for Spravato in Arizona?
Our Scottsdale outpatient psychiatry center combines advanced technology with physician-led care:
- Board-Certified Psychiatric Oversight – Every Spravato treatment is supervised by licensed psychiatry providers with expertise in complex mood disorders.
- REMS-Certified Spravato Clinic – We meet all federal safety and monitoring requirements for esketamine administration.
- Comfort-Focused Medical Suites – Patients receive treatment in a calm, private setting designed to support emotional safety and relaxation.
- Integrated Depression Care – Spravato can be combined with TMS therapy, medication management, and psychotherapy for comprehensive recovery.
- Insurance-Focused Access – Our team assists with authorization and coordination with major commercial payors when available.
Who May Benefit From Spravato Therapy?
Spravato may be appropriate for individuals who:
- Have failed two or more antidepressant trials
- Experience chronic or severe major depressive disorder
- Struggle with suicidal thoughts despite ongoing care
- Have not responded to traditional medication alone
- Need a rapid-acting intervention under psychiatric supervision
Safe, Structured Outpatient Spravato Program
Each Spravato session at Scottsdale TMS includes:
- Pre-treatment medical screening
- Supervised self-administration of esketamine nasal spray
- Continuous monitoring of blood pressure, mood, and vital signs
- Post-treatment recovery observation
- Ongoing psychiatric follow-up and care coordination
Our goal is not only symptom relief, but long-term stabilization and restored quality of life through advanced, evidence-based depression treatment in Scottsdale, Arizona.
